The number of adults with diabetes is raised from 108 million of 1980 to 422 million of 2014, worldwide. The stronger predictors of in-hospital mortality for older patients admitted in general wards were glycemia level ≥ 250 mg/dL, Barthel Index ≤ 40, CIRS-SI, and male sex. Regression analysis showed a strong association between in-hospital death and glycemia ≥ 250 mg/dL (OR 2.07 ), Barthel Index ≤ 40 (3.28),ĬIRS-SI (1.87), and male sex (1.54). In-hospital mortality rate was 9.2% and 5.1% in subjects with glycemia ≥ 250 and < 250 mg/dL, respectively ( p = 0.0010). These patients had a significantly lower Barthel Index ( p = 0.0249), higher CIRS-SI and CIRS-CI scores ( p = 0.0025 and p = 0.0013, respectively), and took more drugs. Compared to subjects with lower glycemia level, patients with glycemia ≥ 250 mg/dL showed higher rates of male sex, smoke and class III obesity. Of the 4714 elderly patients hospitalized, 361 had a glycemia level ≥ 250 mg/dL at admission. Mortality rates were assessed in hospital 3 and 12 months after discharge. Socio-demographic data, reason for hospitalization, diagnoses, treatment, severity and comorbidity indexes (Cumulative Illness rating Scale CIRS-SI and CIRS-CI), renal function, functional (Barthel Index), and cognitive status (Short Blessed Test) and mood disorders (Geriatric Depression Scale) were recorded. Patients were recruited during four index weeks of a year.
Methodsĭata were collected from an active register of 102 internal medicine and geriatric wards in Italy (RePoSi project). We assessed the effects on mortality of hyperglycemia, disability, and multimorbidity at admission in internal medicine ward in patients aged ≥ 65 years. The association between hyperglycemia at hospital admission and relevant short- and long-term outcomes in elderly population is known.
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